第四十四卷(2015)
黏多醋症與 POU1f1 基因型對努比亞山羊生長性能表現之分析
顏念慈(1) 陳若菁(1) 陳元諭(2) 吳昇陽(1) 林德育(1) 賴永裕(1) 陳佳萱(1) 張秀攀(2) 朱賢斌(1) 吳明哲(1)
(1)行政院農業委員會畜產試驗所 (2)國立屏東科技大學動物科學與畜產系
本試驗之目的為利用黏多醋症(Mucopolysaccharidosis,G6S)與腦下垂體特異性轉錄因子 (pituitary transcription factor, POU1f1)的基因型，對 63 頭(14 公，49 母)努比亞山羊的 生長性狀與體型測量值表現進行評估，生長性狀包括出生重、3 月齡(離乳)、6 月齡及 12 月齡之體重、體長、體高、胸圍;另計算從出生至各年齡的平均日增重，初步結果:G6S 基因型正常型 AA 與雜合型 AB 兩者之間，經性別校正後各性狀皆無顯著差異，若考慮 POU1f1 基因型與性別母，在 3 月齡體長、6 月齡體重、6 月齡體高及出生至 6 月齡日增重等性狀，基因型 CT 的個體都顯著高於 CC 個體，但 G6S AB POU1f1 CC 個體 6 月 齡體長顯著大於 G6S AA POU1f1 CC，G6S AB POU1f1 CC 與 G6S AA POU1f1 CT 個體間各性狀無差異，綜合上述結果顯示 POU1f1 與 G6S 基因型對母努比亞山羊生長性狀有 影響，可供未來努比亞山羊生長性能基因選種之參考。
關鍵語:生長性能、基因型、努比亞山羊
ANALYSIS OF GENOTYPE IN MUCOPOLYSACCHARIDOSIS AND POU1f1 WITH GROWTH PERFORMANCE OF NUBIAN GOAT
N. T. Yen(1), J. C. Chen(1), P. Y. Chen(2), S. Y. Wu(1), D. Y. Lin(1), Y. Y. Lai(1), C. H. Chen(1), H. L. Chang(2), H. P. Chu(1) and M. C. Wu(1)
(1) Livestock Research Institute, Council of Agriculture, Executive Yuan (2) Department of Animal Science, National Pingtung University of Science and Technology
The aim of this study was to apply the genotypes of Mucopolysaccharidosis (G6S) and pituitary transcription factor (POU1f1) genes to evaluate its relationship with growth performance of 65 (14 male, 49 female) Nubian goat. The growth performance included body weight at birth, and body weight, body length, withers height, and chest girth at 3-month-age, 6-month-age and 12-month-age, respectively. The average daily gain (ADG) between at birth and vary age periods was also calculated. The preliminary results, there were no significant difference between two G6S genotypes, normal type AA and heterozygous type AB at all growth traits of Nubian goat from the data adjusted with sex factor. If we considered the genotype of POU1f1 in female Nubian goat, individuals with genotype POU1f1 CT were significant higher than with POU1f1 CC in the following traits: body length at 3-month-age, body weigh at 6-month-age, withers height at 6-month-age, and ADG from birth to 6-month-age, respectively. But the body length at 3-month-age of individuals with genotype G6S AB, POU1f1 CC was significant higher than with genotype G6S AA, POU1F1 CC. There was no significant difference between individual with G6S AB, POU1F1 CC and with G6S AA, POU1f1 CT at all growth traits of Nubian goat. POU1f1 and G6S genotypes affected growth traits of female Nubian goats. The results are potentially useful in rapid growth selection program for Nubian goat farmer in the future.
Key Words: Growth performance, Genotype, Nubian goat
  
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