第四十七卷(2018)
127.台灣登錄種羊黏多醣症基因型頻率
顏念慈 林德育 陳若菁 陳水財 范耕榛 周宜靜 莊璧華 廖曉涵 吳明哲
行政院農業委員會畜產試驗所
黏多醣症第三型（G6S）是山羊的隱性遺傳疾病。檢測 8家 982 頭登錄種羊之黏多醣症第三型（G6S）基因型，完成8場 (畜試所營養組、恆春分所、花蓮種畜繁殖場、澎湖工作站、大鵬乳羊畜牧場、成立種肉羊畜牧場、神來畜牧場及晨光畜牧場)，包括303頭努比亞、494頭阿爾拜因、89頭撒能、4頭波爾、44頭台灣黑山羊、32頭吉安山羊及16頭墾丁山羊，試驗結果，除阿爾拜因有7頭母為G6S AB雜合型外，其他羊隻皆為G6S AA正常型，雜合型羊隻已建議畜主考慮淘汰。本試驗所得結果比林等2008年的報告 G6S非正常型頻率低很多 (0.7 % 比 5.9 %)，顯示十年來養羊產業已應用此基因選種技術進行種羊選種，將有助於整體生產體系之效率提高。
關鍵語：登錄種羊、黏多醣症、基因型頻率
Frequency of mucopolysaccharidosis IIID genotypes of registered breeding goat in Taiwan
N. T. Yen, D.Y. Lin, J. C. Chen, S. T. Chen, G. J. Fan, P. H. Chuang, X. H. Liu
Livestock Research Institute, Council of Agriculture, Executive Yuan
Caprine mucopolysaccharidosis IIID, or N-acetylglucosamine 6-sulfatase deficiency （G6S）, is a recessive inherited disorder of goat. There were 982 goat DNA samples tested from 8 herds of 303 Nubians, 494 Alpines, 89 Saanens, 4 Boers, 44 Taiwan Black Goats, 32 Ji'an goats and 16 Kenting goats. The result showed that except for Alpine goat, there are 7 female goats in the G6S AB heterozygous type, the other goats are all G6S AA normal type. Goats with heterozygous type have been advised to consider elimination. The frequency of abnormal G6S genotypes in this experiment was much lower than reported by Lin et al. in 2008 (0.7 % vs 5.9 %), indicating that the goat industry has applied this gene selection technique for breeding goat in the past ten years to improve the efficiency of overall production system in Taiwan.
Key words: Registered breeding goat, Mucopolysaccharidosis, Frequency of Genotype
  
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