第五十二卷(2023)
144. 蘭嶼豬生物醫學影像之建構
楊鎮榮(1) 廖御靜(1)
(1)農業部畜產試驗所遺傳生理組
蘭嶼豬（Lanyu pigs）為臺灣生醫用小型豬種，已廣泛應用於基礎研究、心血管疾病、組織工程與藥理學等研究，對暸解與治療人類疾病具有相當大之潛力。然而，對蘭嶼豬的解剖構造暸解有限，加上解剖圖鑑與生物醫學影像資料的缺乏，使動物試驗無法精準有效的操作。本研究建立蘭嶼豬公豬與母豬腦、腹部脂肪與生殖器官之磁振造影（magnetic resonance imaging, MRI）影像，以及全身之電腦斷層掃描（computed tomography, CT）影像，建立完整生物醫學影像資料庫。此影像為連續切面並可重構為 3D 結構，於電腦上可即時查閱，有利於動物試驗時精準有效的操作，並有效減少試驗動物使用量。未來此資料庫將線上開放使用，對試驗研究與教學使用將有相當大之助益。
關鍵語：蘭嶼豬、磁振造影、電腦斷層掃描
Establishment of biomedical imaging in Lanyu pigs
J. R. Yang(1) and Y. J. Liao(1)
(1)Genetics and Physiology 0ivision, Taiwan Livestock Research Institute, Ministry of Agriculture
Lanyu pigs are a miniature swine breed used extensively in Taiwan for biomedical research, such as in the fields of basic research, cardiovascular diseases, tissue engineering, and pharmacology. They hold significant potential for understanding and treating human diseases. However, the understanding of the anatomical structures of Lanyu pigs is limited. Furthermore, the lack of anatomical atlases and biomedical imaging data hampers precise and effective procedures during animal research. Here, male and female Lanyu pigs are subjected to magnetic resonance imaging (MRI) of the brains, abdominal fat, and reproductive organs, and to computed tomography (CT) of whole bodies. This comprehensive biomedical imaging database consists of sequential cross- sections that can be reconstructed into 30 structures. The imaging allows for real-time review on a computer, promoting precise and efficient procedures during animal research and reducing the number of animals used. This database will be available online in the future, offering substantial benefits for experimental research and educational purposes.
Key Words: Lanyu pigs, Magnetic resonance imaging, Computed tomography
  
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